Subtyping of Hepatitis C virus using Bioinformatics and Mass Spectrometry Data lecture at UJ by Dr. Reaz Uddin (University of Karachi - Pakistan)

The seminars committee at the Chemistry Department at the University of Jordan invites you for a lecture titled:
تتشرف لجنة الندوات في قسم الكيمياء/ الجامعة الأردنية بدعوتكم لحضور محاضرة علمية بعنوان:
 
Subtyping of Hepatitis C virus using Bioinformatics and Mass Spectrometry Data
 
Dr. Reaz Uddin
Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences
 University of Karachi - Pakistan
 
د. رياز الدين
مركز د. بانجواني للطب الجزيئي وابحاث الدواء والمركز العالمي للبحوث الكيميائية والبيولوجية
جامعة كراتشي - الباكستان
Place: Seminar Room, Department of Chemistry
المكان : قاعة النشاطات / قسم الكيمياء
 
Date & Time: Sunday 12/11/2017 at 11:00 am
الزمان: الاحد 11/11/2017 في تمام الساعة 11:00 صباحا
 
 
 
ABSTRACT
Hepatitis C virus is still a primary cause of chronic liver disease and considered as a global health problem which often lead to hepatocellular carcinoma and liver cirrhosis. In the absence of successful vaccine against HCV, it is expected that the Virus may cause infection to a much larger proportion of the global population and can turn them as carriers. The HCV belonged to the hepacivirus genus of the Flaviviridae family. There are various types of HCV classifies on the basis of genetic diversity. In the current study we used the genomics data available for various subtypes and used the Bioinformatics approaches to identify the mass signatures associated with the specific subtype of HCV. Those mass signatures when combined with the mass spectrometry data gives us the direct confirmation of the type of the HCV. The method described in this study provided the alternative approach to classify the virus into their subtypes using Bioinformatics and mass spectrometry data alone and by pass the conventional molecular based PCR methods with appreciable sensitivity.
 
الدعوة عامة